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Paul M. Lieberman, Ph.D., is a researcher and director of the Center for Chemical Biology and Translational Medicine at The Wistar Institute in Philadelphia.〔(【引用サイトリンク】url=http://www.wistar.org/our-science/scientists/paul-m-lieberman-phd )〕〔(【引用サイトリンク】url=http://www.med.upenn.edu/apps/faculty/index.php/g20000320/p4209099 )〕〔(【引用サイトリンク】url=http://www.vironika.com/Vironika/Management.html )〕〔(【引用サイトリンク】url=http://www.newswise.com/articles/the-wistar-institute-and-university-of-the-sciences-announce-mcneil-professorship-to-lead-collaborative-center )〕 He is also the Hilary Koprowski, M.D., Endowed Professor, the McNeil Professor of Molecular Medicine and Translational Research , a professor in the Gene Expression and Regulation Program , and the Scientific Director of the Protein Expression and Libraries Facility at Wistar. Lieberman's research focus is how certain viruses are linked to cancer, particularly Epstein-Barr virus. Lieberman and his laboratory collaborated with Memorial Sloan-Kettering Cancer Center to develop the first annotated atlas of the genome of Epstein-Barr virus.〔(【引用サイトリンク】url=http://www.sciencedaily.com/releases/2012/08/120823143747.htm )〕 In 2011, Liberman received a Seeding Drug Discovery Award from Wellcome Trust for $4.7 million to develop a drug against Epstein-Barr virus-related cancers. This was the first project to receive such an award from the United Kingdom-based trust.〔(【引用サイトリンク】url=http://www.wistar.org/wistar-today/wistar-wire/2011-12-15/wistar-receives-47-million-wellcome-trust )〕 Lieberman serves as the president of the International Association for Research on Epstein-Barr virus and Associated Diseases.〔(【引用サイトリンク】url=https://www.bcm.edu/ebvassociation/ebv-officers.htm )〕 ==Select publications== * Deng Z, Glousker G, et al., Lieberman PM, Tzfati, Y. Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome. PNAS 2013. * Dheekollu J, Chen HS, Kaye KM, Lieberman PM. Timeless-dependent DNA replication-coupled recombination promotes Kaposi’s Sarcoma-associated herpesvirus episome maintenance and terminal repeat stability. J. Virology. 2013 Apr 87(7):369. * Deng Z, Wang Z, Stong N, Plasschaert R, et al. Riethman H, and Lieberman PM. A role for CTCF and cohesion in subtelomere chromatin organization, TERRA transcription, and telomere end protection. EMBO J. 2012 Nov 31(21):4165. * Kang H, Cho H, Sung GH, Lieberman PM. CTCF regulates Kaposi’s sarcoma-associated herpesvirus latency transcription by nucleosome displacement and RNA polymerase programming. Journal of Virology 2013 Feb 87(3)1789. * Arvey A, Tempera I, Tsai K, Chen HS, Tikhmyanova N, Klichinsky M, Leslie C, Lieberman PM. An atlas of the Epstein-Barr virus transcriptome and epigenome reveals host-virus regulatory interactions. Cell Host Microbe 2012 Aug 12(2)233. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Paul Lieberman」の詳細全文を読む スポンサード リンク
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